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发表时间:2021-03-09阅读次数:2022次

俞寿云

南京大学化学化工学院教授,博士生导师,课题组负责人。

2001年毕业于南京大学化学化工学院,获得学士学位。同年进入中科院上海有机化学研究所攻读博士,师从马大为研究员,2006年6月获得博士学位,并留所任助理研究员。在这期间主要从事具有重要生理活性天然产物全合成的研究工作。2007年10月至2010年4月,在宾夕法尼亚大学Jeffrey Bode教授小组进行博士后研究,主要从事β-氨基酸和多肽的合成以及生物学评价等方面的工作。2010年4月到8月,在上海有机化学研究所任副研究员,主要从事天然产物全合成和不对称催化的研究。2010年9月,被聘为南京大学化学化工学院副教授,课题组长。2012年增选为博士生导师。2016年晋升为正教授。主要开展有机光化学,自由基化学及天然产物合成的研究。

  

教育经历

2001/8 – 2006/7  有机化学博士

 中国科学院上海有机化学研究所生命有机国家重点实验室

  导师: 马大为 研究员                  

1997/9 – 2001/7  学士

 南京大学化学化工学院

  

工作经历

2016至今教授

 南京大学化学化工学院

2010/9 - 2015/12  副教授博导

  南京大学化学化工学院

2010/4 – 2010/8  副研究员

 中国科学院上海有机化学研究所生命有机国家重点实验室

2007/10 – 2010/4  博士后

 美国宾夕法尼亚大学化学系

合作导师: Prof. Jeffrey W. B

2006/7 – 2007/9  助理研究员

 中国科学院上海有机化学研究所生命有机国家重点实验室

  

科研方向


 1. 有机光化学; 2. 自由基化学; 3. 不对称催化; 4. 天然产物合成的研究

科研项目


科研成果

 1.       Xiaoyang Sun and Shouyun Yu,* Synthesis of Polysubstituted (Hetero)aromatic Compounds Using Visible-Light-Promoted Radical Triple Bond Insertions. Chin. J. Org. Chem.2016,36, 239-247.

 孙晓阳, 俞寿云,* 可见光促进的自由基型三重键插入反应在多取代芳(杂)环合成中的应用. 有机化学, 2016,36, 239-247.

 2.       Hao Wang, Yuanzheng Cheng and Shouyun Yu,* Visible-light-promoted and photocatalyst-free trifluoromethylation of enamides. Sci. China Chem. 2016,59, 195-198.

 3.       Kun Tong, Tianyi Zheng, Yan Zhang* and Shouyun Yu,* Synthesis of ortho-(Fluoro)alkylated Pyridines via Visible Light-Promoted Radical Isocyanide Insertion. Adv. Synth. Catal. 2015,357, 3681-3686.

 4.       Xiao-De An and Shouyun Yu,* Direct Synthesis of Nitriles from Aldehydes Using an O‑Benzoyl Hydroxylamine (BHA) as the Nitrogen Source. Org. Lett.2015,17, 5064-5067.

 5.       Qixue Qin, Daan Ren and Shouyun Yu,* Visible-Light-Promoted Chloramination of Olefins with N-chlorosulfonamide as Both Nitrogen and Chlorine Sources. Org. Biomol. Chem.2015,13, 10295-10298.

 6.       Hao Wang, and Shouyun Yu,* Synthesis of Isoquinolones Using Visible-Light-Promoted Denitrogenative Alkyne Insertion of 1,2,3-Benzotriazinones. Org. Lett.2015,17, 4272-4275.

 7.       Xiao-De An and Shouyun Yu,* Visible-Light-Promoted and One-Pot Synthesis of Phenanthridines and Quinolines from Aldehydes and O-Acyl Hydroxylamine. Org. Lett.2015,17, 2692-2695.

 8.       Yuanzheng Cheng, Xiangai Yuan, Jing Ma* and Shouyun Yu,* Direct Aromatic C-H Trifluoromethylation via an Electron−Donor–Acceptor Complex. Chem. Eur. J.2015,21, 8355-8359.

 9.       Qixue Qin and Shouyun Yu,* Visible-Light-Promoted Remote C(sp3)−H Amidation and Chlorination. Org. Lett.2015,17, 1894-1897.

 10.   Heng Jiang, Xiaode An, Kun Tong, Tianyi Zheng, Yan Zhang* and Shouyun Yu,* Visible-Light-Promoted Iminyl Radical Formation from Acyl Oximes: A Unified Approach to Pyridines, Quinolines and Phenanthridines. Angew. Chem. Int. Ed. 2015, 54, 4055-4059.

 11.   Jiajia Guo and Shouyun Yu,* Enantioselective Synthesis of Benzoindolizidine Derivatives Using Chiral Phase-Transfer Catalytic Intramolecular Domino Aza-Michael Addition/Alkylation. Org. Biomol. Chem.2015,13, 1179-1186.

 12.   Xiaoyang Sun, Jiahong Li, Yunpeng Ni, Daan Ren, Zhentao Hu and Shouyun Yu,* Synthesis of Fused Quinoline and Quinoxaline Derivatives Enabled by Domino Radical Triple Bond Insertions. Asian J. Org. Chem. 2014,3, 1317-1325.   

13.   Shuanghua Cheng and Shouyun Yu,* Enantioselective Synthesis of 3-Substituted 1,2-Oxazinanes via Organocatalytic Intramolecular Aza-Michael Addition. Org. Biomol. Chem.2014, 12, 8607-8610.

 14.   Ruzhi Wang, Heng Jiang, Yuanzheng Cheng, Adnan A. Kadi, Hoong-Kun Fun, Yan Zhang* and Shouyun Yu,* Somophilic Isocyanide Insertion: Synthesis of 6-Arylated and 6-Trifluoro­methylated Phenanthridines. Synthesis2014, 46, 2711-2726.

 15.   Yuanzheng Cheng, Xiangai Yuan, Heng Jiang, Ruzhi Wang, Jing Ma,* Yan Zhang* and Shouyun Yu,* Regiospecific Synthesis of 1-Trifluoromethylisoquinolines Enabled by Photoredox Somophilic Vinyl Isocyanide Insertion. Adv. Synth. Catal. 2014,356, 2859-2886.

 16.   Qixue Qin and Shouyun Yu,* Visible-Light-Promoted Redox Neutral C−H Amidation of Heteroarenes with Hydroxylamine Derivatives. Org. Lett.2014,16, 3504-3507.

 17.   Xiaoyang Sun and Shouyun Yu,* Visible-Light-Mediated Fluoroalkylation of Isocyanides with Ethyl Bromofluoroacetates: Unified Synthesis of Mono- and Difluoromethylated Phenanthridine Derivatives. Org. Lett.2014,16, 2938-2941.

18.   Heng Jiang, Yuanzheng Cheng, Ruzhi Wang, Yan Zhang* and Shouyun Yu,* Synthesis of isoquinolines via visible light-promoted insertion of vinyl isocyanides with diaryliodonium salts. Chem. Commun.2014,50, 6164-6167.

19.   Shuanghua Cheng, Lili Zhao and Shouyun Yu,* Enantioselective Synthesis of Azaflavanones Using Organocatalytic 6-endo Aza-Michael Addition. Adv. Synth. Catal.2014, 356, 982-986.

 20.   Jiajia Guo, Xiaoyang Sun and Shouyun Yu,* Diastereoselective Synthesis of Epoxide-fused Benzoquinolizidine Derivatives Using Intramolecular Domino Aza-Michael Addition/Darzens Reaction. Org. Biomol. Chem.2014,12, 265-268.

 21.   Heng Jiang, Yuanzheng Cheng, Ruzhi Wang, Mengmeng Zheng, Yan Zhang* and Shouyun Yu,* Synthesis of 6-Alkylated Phenanthridine Derivatives using Photoredox Neutral Somophilic Isocyanide Insertion. Angew. Chem. Int. Ed.2013,52, 13289-13292.

 22.   Yuanzheng Cheng, Heng Jiang, Yan Zhang and Shouyun Yu,* Isocyanide Insertion: De Novo Synthesis of Trifluoromethylated Phenanthridine Derivatives. Org. Lett. 2013,15, 5520-5523.

 23.   Heng Jiang, Yuanzheng Cheng, Yan Zhang* and Shouyun Yu,* De Novo Synthesis of Polysubstituted Naphthols and Furans Using Photoredox Neutral Coupling of Alkynes with 2-Bromo-1,3-Dicarbonyl Compounds. Org. Lett. 2013,15, 4884-4887.

 24.   Heng Jiang, Yuanzheng Cheng, Yan Zhang* and Shouyun Yu,* Sulfonation and Trifluoromethylation of Enol Acetates with Sulfonyl Chlorides Using Visible-Light Photoredox Catalysis. Eur. J. Org. Chem.2013, 5485-5492.

 25.   Hanbin Liu, Chuanqi Zeng, Jiajia Guo, Mengyao Zhang and Shouyun Yu,* Enantioselective Synthesis of 2-Substituted Pyrrolidines via Domino Cross Metathesis/Intramolecular aza-Michael Addition. RSC Adv.2013, 3, 1666-1668.

 26.   Heng Jiang, Xuejiao Chen, Yan Zhang* and Shouyun Yu,* C-H Functionalization of Enamides: Synthesis of b-Amidovinyl Sulfones via Visible-Light Photoredox Catalysis. Adv. Synth. Catal. 2013,355, 809-813.

 27.   Heng Jiang, Chengmei Huang, Jiajia Guo, Chuanqi Zeng, Yan Zhang* and Shouyun Yu,* Direct C-H Functionalization of Enamides and Enecarbamates by Using Visible-Light Photoredox Catalysis. Chem. Eur. J.2012,18, 15158-15166.

 28.   Chuanqi Zeng, Hanbin Liu, Mengyao Zhang, Jiajia Guo, Shunchao Jiang and Shouyun Yu,* Enantioselective Synthesis of Cryptopleurine and Boehmeriasin A via Organocatalytic Intramolecular Aza-Michael Addition. Synlett2012,23, 2251-2254.

 29.   Fengtao Zhou, Jiajia Guo, Jianguang Liu, Ke Ding, Shouyun Yu* and Qian Cai,* Copper-Catalyzed Desymmetric Intramolecular Ullmann C-N Coupling:An Enantioselective Preparation of Indolines. J. Am. Chem. Soc. 2012,134, 14326-14329.

  

获奖

1. 南京大学‘登峰人才支持计划(B层次)’,2014

2. Thieme Chemistry Journals Award 2012

3. 2007年国家自然科学奖,二等奖(排名第四)

  

  

小组成员