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发表时间:2021-03-11阅读次数:2022次



程旭  教授


https://hysz.nju.edu.cn/chengxu/


教育经历

1996.9-2000.8:    南开大学化学系,获得本科学位。
2000.9-2005.11:南开大学元素有机化学研究所,获得博士学位,研究方向为手性催化剂的设计和对映选择性催化反应,指导教师:周其林教授。

工作经历

2005.12-2008.11:德国Max-Planck煤炭研究所,博士后
2008.12-2009.12: 美国德克萨斯州立Austin分校,博士后
2010.1至2012.6: 美国普度大学化学系,博士后
2012.9至今:     南京大学大学化学化工学院,副教授

科研方向

 
 

科研项目

国家自然科学基金面上项目21572099

江苏省自然科学基金面上项目BK20151379

科研成果

(26) Guoqiang Wang,a Jia Cao,a,cLiuzhou Gao,a Wenxin Chen,b Wenhao Huang,b XuCheng,b,d* and Shuhua Lia*

Metal-Free Synthesis of C-4 SubstitutedPyridine Derivatives Using Pyridine-boryl Radicals via a RadicalAddition/Coupling Mechanism: A Combined Computational and Experimental Study

J. Am. Chem. Soc. 2017139, 3904-3910 .

(25)  Wenhao Huang, Xu Cheng*

Hantzsch esters as multifunctional reagentsin visible-light photoredox catalysis

Synlett201728, 148-158, Invited Synpact.

(24) Wenhao Huang, Wenxin Chen, Guoqiang Wang, Jin Li, Xu Cheng,* and Guigen Li

Thiyl-Radical-Catalyzed Photoreductive Hydrodifluoroacetamidation of Alkenes with Hantzsch Ester as Multifunctional Reagent

ACS Catal., 2016, 6, 7471-7474.

(23) Jin Li, Jingzhi Chen, Wei Jiao, Guoqiang Wang, Ying Li, Xu Cheng,* Guigen Li

Difluoroalkylation/C-Hannulation cascade reaction induced by visible-light photoredox catalysis

J. Org. Chem., DOI: 10.1021/acs.joc.6b01825

(22) Wenxin Chena, Zheng Liua, Jiaqi Tianb, Jin Lia, Jing Mab*, Xu Chenga*, Guigen Lia,c

Building Congested Ketone: Substituted Hantzsch Ester and Nitrile as Alkylation Reagents in Photoredox catalysis

J. Am. Chem. Soc., 2016, 138, 12312–12315

(21) Jie Cheng, Xia Deng, Guoqiang Wang, Ying Li, Xu Cheng*,and Guigen Li

Intermolecular C–H Quaternary Alkylation ofAniline Derivatives Induced by Visible-Light Photoredox Catalysis

Org. Lett. 2016, 18, 4538–4541

(20) Wenxin Chen, Huachen Tao, Wenhao Huang, Guoqiang Wang, Shuhua Li,* Xu Cheng,* Guigen Li

Hantzsch Ester as a Photosensitizer for Visible-Light-Induced Debromination of Vicinal Dibromo Compounds

Chem. Eur. J. 2016, 22, 9546-9550.

(19)  Jun Fei, Zhen Wang, Zheren Cai, HaoSun, Xu Cheng*

Synthesis of α-TertiaryAmine Derivatives by Intermolecular Hydroamination of Unfunctionalized Alkeneswith Sulfamates under Trifluoromethanesulfonic Acid Catalysis 

Adv. Synth. Catal. 2015, 357, 4063357.

(18) Zheng Liu, Yi Zhang, Zheren Cai, Hao Sun, and Xu Cheng*

Photoredox Removal of p-Methoxybenzyl Ether Protecting Group withHydrogen Peroxide as Terminal Oxidant

Adv. Synth. Catal. 2015, 357, 589

(17) Yi Zhang, Yuchi Dai, Guigen Li, Xu Cheng*

The Catalytic Synthesis of Carboniolamide:the Role of sp3 Hybridized Oxygen

Synlett 2014, 25, 2644.

(16) Yi Zhang, Zhihao Zhong, Yingmei Han, Ruirui Han, Xu Cheng*

A convenientsynthesis of bisamides with BF etherate ascatalyst

Tetrahedron. 2013, 69, 11080.

(15) Arun K. Ghosh*, Xu Cheng, Bing Zhou

Enantioselective Total Synthesis of (+)-Lithospermic Acid

Org. Lett. 2012,14, 5046-5049.

(14) Arun K. Ghosh*, Xu Cheng, Ruoli, Bai, Arni Hamel

Total Synthesis of Poetent Antitumor Macrolide, (-)-Zampanolide: An Oxidative C-H Bond Activation-Based Strategy.

Eur. J. Org.Chem. 2012, 4130.

(13) Arun K. Ghosh*, Xu Cheng,

Synthesis of Functionalized 4-Methylenetetrahydropyrans by Oxidative C-H Activation of Allyl or Benzyl Ethers.

Tetrahedron Lett. 2012, 53, 2568-2570.

(12) Xu Cheng, Nicole L. Harzdorf, Zin Khaing, Danby Kang, Andrew M. Camelio, Travis Shaw, Christine E. Schmidt, and Dionicio Siegel*

Neuronal Growth Promoting Sesquiterpene-Neolignans;Syntheses and Biological Studies

Org. Biomol. Chem. 2012,10, 383.

(11) Arun K. Ghosh*, Xu Cheng

Enantioselective Total Synthesis of (−)-Zampanolide, a Potent Microtubule-Stabilizing Agent

Org. Lett. 2011, 13, 4108. (one of most accessed papers in August)

(10) Xu Cheng, Nicole L. Harzdorf, Travis Shaw and Dionicio Siegel*

Biomimetic Syntheses of the Neurotrophic Natural Products Caryolanemagnolol and Clovanemagnolol

Org. Lett. 2010, 12, 1304.

(9) Xu Cheng, Sreekumar Vellalath, Richard Goddard, and Benjamin List*

Direct Catalytic Asymmetric Synthesis of Cyclic Aminals from Aldehydes

J. Am. Chem. Soc. 2008,130, 15786.

(8) Nolwenn J. A. Martin, Xu Cheng, and Benjamin List*

Organocatalytic Asymmetric Transferhydrogenation of β-Nitroacrylates: Accessing β2-Amino Acids

J. Am. Chem. Soc. 2008, 130, 13862.

(7) Xu Cheng, Richard Goddard, Gernot Buth, Benjamin List*

Direct Catalytic Asymmetric Three-Component Kabachnik-Fields Reaction

Angew. Chem. Int. Ed. 2008, 47, 5079.

(6) Ji-Chao Yan, Xu Cheng, Qi-Lin Zhou*, and Jian Pei*

Chiral Polyfluorene Derivatives: Synthesis, Chiroptical Properties, and Investigation of the Structure−Property Relationships

Macromolecules. 2007,40, 832.

(5) Xu Cheng, Jian-Hua Xie, Sheng Li, Qi-Lin Zhou*

Asymmetric Hydrogenation of a,β-Unsaturated Carboxylic Acids Catalyzed by Ruthenium(II) Complexes of Spirobifluorene Diphosphine (SFDP) Ligands 

Adv. Synth. Catal. 2006, 348, 1271.

(4) Xu Cheng, Shou-Fei Zhu, Xiang-Chen Qiao, Pu-Cha Yan, Qi-Lin Zhou*

A general synthetic route to chiral dihydroxy-9,9′-spirobifluorenes

Tetrahedron. 2006, 62, 8077.

(3) Jian-Hua Xie, Sheng Liu, Xiang-Hong Huo, Xu Cheng, Hai-Feng Duan, Bao-Min Fan, Li-Xin Wang, Qi-Lin Zhou*

Ru-II-SDP-complex-catalyzed asymmetric hydrogenation of ketones. Effect of the alkali metal cation in the reaction

J. Org. Chem. 2005, 70, 2967.

(2) Xu Cheng, Qi Zhang, Jian-Hua Xie, Qi-Lin Zhou*

Highly Rigid Diphosphine Ligands with Large Dihedral Angle Based on Chiral Spirobifluorene Backbone

Angew. Chem. Int. Ed. 2005, 44, 1118.

(1) Xu Cheng, Guo-Hua Hou, Jian-Hua Xie, Qi-Lin Zhou*

Synthesis and optical resolution of 9,9'-spirobifluorene-1, 1'-diol 
Org. Lett. 2004, 6, 2381

获奖

Thieme Chemistry Jounral Award 2017

教授课程

化院应化专业有机化学基础课

基础有机化学实验主任

小组成员

李进,黄文浩,戴鹏(联合),刘旭,谷芳军,陈靖之